MATERIALS AND METHODS FOR TREATING AND MANAGING ANGIOGENESIS-MEDIATED DISEASES

摘要

MATERIALS AND METHODS FOR TREATING AND MANAGING ANGIOGENESIS-MEDIATED DISEASESAbstract Disclosed herein are materials and methods suitable for treating sites of pathological angiogenesis and abnormal neovascularization. Sites ofpathological angiogenesis or abnormal neovascularization can be treated bycontacting a surface at or adjacent or in the vicinity of an area of pathological angiogenesis or abnormal neovascularization with an implantable material. Theimplantable material comprises a biocompatible matrix and cells and is in an amount effective to treat the affected site. The composition can be a flexibleplanar material or a flowable composition. Diseases susceptible to treatment withthe present invention include, for example, macular degeneration, rheumatoid arthritis, psoriasis, psoriatic arthritis, systemic inflammatory diseases, andtreatment of tumors by surgical resection, radiation therapy or chemotherapy. (No suitable figure)