发明名称 |
IMMUNOSUPPRESSION MODULATING COMPOUNDS |
摘要 |
<p>The present invention provides immunosuppression compounds capable of inhibiting the programmed cell death 1 (PDl) signalling pathway. The present invention further provides peptide based compositions for treatment of cancer or treatment of infections via immunopotentiation caused by inhibition of immunosuppressive signaling induced by PD-1, PD-L1, or PD-L2 and therapies using them, immunopotentiative substrates included as the active ingredient. Further, the invention provides an application of the compositions containing the peptide moieties for preventive and/or therapeutic agents for cancer, cancer metastasis, immunodeficiency, an infectious disease or the like and an application of peptide moieties as a testing or diagnostic agent or a research agent for such a disease.</p> |
申请公布号 |
CA2803859(A1) |
申请公布日期 |
2011.12.29 |
申请号 |
CA20112803859 |
申请日期 |
2011.06.27 |
申请人 |
AURIGENE DISCOVERY TECHNOLOGIES LIMITED |
发明人 |
SASIKUMAR, POTTAYIL GOVINDAN NAIR;RAMACHANDRA, MURALIDHARA;VADLAMANI, SURESH KUMAR;VEMULA, KOTESWARA RAO;SATYAM, LEENA KHARE;SUBBARAO, KRISHNAPRASAD;SHRIMALI, RAJEEV K.;KANDEPU, SREENIVAS |
分类号 |
A61K38/17;C07K14/705 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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地址 |
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