发明名称 Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions
摘要 Provided are compounds, pharmaceutical compositions and methods of treating or preventing disorders associated with NMDA receptor activity, including schizophrenia, Parkinson's disease, cognitive disorders, depression, neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds of the general Formulas A-E, and pharmaceutically acceptable salts, esters, prodrugs or derivatives thereof are disclosed.
申请公布号 US2011319416(A1) 申请公布日期 2011.12.29
申请号 US201013146225 申请日期 2010.01.28
申请人 TRAYNELIS STEPHEN F.;LIOTTA DENNIS C.;MOSLEY CARA;ACKER TIMOTHY M.;ZIMMERMAN SOMMER;EMORY UNIVERSITY 发明人 TRAYNELIS STEPHEN F.;LIOTTA DENNIS C.;MOSLEY CARA;ACKER TIMOTHY M.;ZIMMERMAN SOMMER
分类号 A61K31/5375;A61K31/27;A61K31/40;A61K31/404;A61K31/426;A61K31/428;A61K31/4453;A61K31/4709;A61P7/04;A61P9/10;A61P25/00;A61P25/04;A61P25/08;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P29/00;C07C271/44;C07C333/04;C07D209/08;C07D277/34;C07D277/68;C07D295/205;C07D333/32;C07D401/04 主分类号 A61K31/5375
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