发明名称 |
METHOD OF SCREENING PLACENTAL PROTEINS RESPONSIBLE FOR PATHOPHYSIOLOGY OF PREECLAMPSIA, AND MARKER FOR EARLY DIAGNOSIS AND PREDICTION OF PREECLAMPSIA |
摘要 |
The present invention relates to a method of screening placental proteins responsible for pathophysiology of preeclampsia, and a marker for early diagnosis and prediction of preeclampsia. In accordance with one aspect of the present invention, there is provided a method of screening placental proteins responsible for pathophysiology of preeclampsia by 2D E-proteomics analysis, comprising: isolating placental proteins from a placental tissue; separating the isolated proteins two-dimensionally through 2D electrophoresis; and comparing and analyzing the separated proteins based on scanned gel images and differences in the images between normal placental proteins and preeclamptic placental proteins, wherein the comparison and analysis of the placental proteins based on the scanned gel images and differences in the images are accomplished by selecting proteins with differences of 140% or more between two placentas.
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申请公布号 |
US2011318809(A1) |
申请公布日期 |
2011.12.29 |
申请号 |
US201113154774 |
申请日期 |
2011.06.07 |
申请人 |
PARK WON SUN;KIM NA RI;HAN JIN |
发明人 |
PARK WON SUN;KIM NA RI;HAN JIN |
分类号 |
C12N9/96;C07K14/435;C07K16/18;C12N9/04;C12N9/10;C12N9/50;C12N9/90 |
主分类号 |
C12N9/96 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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