发明名称 NEUROPROTECTIVE COMPOUNDS
摘要 The invention describes the use of (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl-1-naphthalenyl propanoate derivatives, optionally mono- or di-methylated at the carbon in the alpha position of propanoic acid, of formula (I), where R is CH3CH2CO—, (CH3)2CHCO— or (CH3)3CCO—, its hydroxy acid forms and the pharmaceutically acceptable salts of said hydroxy acids, as neuroprotective compounds potentially useful for the prevention and/or treatment of neurodegenerative diseases, or of diseases associated with an unwanted oxidation or of age-associated pathological processes, or of epilepsy, epileptic seizures or convulsions.
申请公布号 US2011319484(A1) 申请公布日期 2011.12.29
申请号 US201013254104 申请日期 2010.03.05
申请人 BURGOS MUNOZ JAVIER SANTOS;RAMOS MARTIN MARIA DEL CARMEN;SIERRA AVILA SALETA;ALFARO SANCHEZ JUAN MARIA;VELASCO ALVAREZ JAVIER;RUMBERO SANCHEZ ANGEL;RAMIREZ MORENO CARLOS;PARQUE TECNOLOGICO DE CIENCIAS DE LA SALUD 发明人 BURGOS MUNOZ JAVIER SANTOS;RAMOS MARTIN MARIA DEL CARMEN;SIERRA AVILA SALETA;ALFARO SANCHEZ JUAN MARIA;VELASCO ALVAREZ JAVIER;RUMBERO SANCHEZ ANGEL;RAMIREZ MORENO CARLOS
分类号 A61K31/366;A61P25/08;A61P25/28 主分类号 A61K31/366
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