The present application relates to a novel HIV-1 envelope glycoprotein which may be utilized as an HIV- 1 vaccine immunogen, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
申请公布号
WO2011109511(A3)
申请公布日期
2011.12.29
申请号
WO2011US26862
申请日期
2011.03.02
申请人
INTERNATIONAL AIDS VACCINE INITIATIVE;PHOGAT, SANJAY, K.;KOFF, WAYNE, C.;KING, CHARLES, RICHTER;WAGNER, DENISE;HOFFENBERG, SIMON