发明名称 |
AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS |
摘要 |
The present invention relates to compounds that have CYP450 inhibiting properties and are therefore useful as boosters of certain drugs, i.e. they are able to increase at least one of the pharmacokinetic variables of certain drugs when co-administered. The invention further provides the use of said compounds as improvers of the bioavailability of certain drugs. Methods for the preparation of the compounds of the invention and pharmaceutical compositions are also provided. |
申请公布号 |
ZA201004025(B) |
申请公布日期 |
2011.12.28 |
申请号 |
ZA20100004025 |
申请日期 |
2010.06.04 |
申请人 |
TIBOTEC PHARMACEUTICALS LTD |
发明人 |
JONCKERS TIM HUGO MARIA;SCHEPENS WIM BERT GRIET;HACHE GEERWIN YVONNE PAUL;HALLENBERGER BEATE SABINE;SASAKI JENNIFER CHIYOMI;BAUMEISTER JUDITH EVA;VAN'T KLOOSTER GERBEN ALBERT ELEUTHERIUS |
分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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