发明名称 Indole derivative having PGD2 receptor antagonist activity
摘要 <p>The present invention relates to a compound of formula (I): &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="42" wi="82" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /&gt;&lt;/Chemistry&gt; wherein the ring A is a pyridine ring; the ring B is a ring of the formula of &lt;Chemistry id="chema02" num="0002"&gt;&lt;Image id="ia02" he="20" wi="127" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" /&gt;&lt;/Chemistry&gt;&lt;Chemistry id="chema03" num="0003"&gt;&lt;Image id="ia03" he="17" wi="102" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" /&gt;&lt;/Chemistry&gt; wherein R&lt;Sup&gt;1&lt;/Sup&gt;, R&lt;Sup&gt;2&lt;/Sup&gt;, R&lt;Sup&gt;3&lt;/Sup&gt; R&lt;Sup&gt;4&lt;/Sup&gt;, R&lt;Sup&gt;5&lt;/Sup&gt;, R&lt;Sup&gt;6&lt;/Sup&gt;, R&lt;Sup&gt;7&lt;/Sup&gt;, R&lt;Sup&gt;8&lt;/Sup&gt;, R&lt;Sup&gt;9&lt;/Sup&gt;, M, Y, L&lt;Sup&gt;1&lt;/Sup&gt;, L&lt;Sup&gt;2&lt;/Sup&gt;, L&lt;Sup&gt;3&lt;/Sup&gt;, n and q are defined as in claim 1 or a pharmaceutically acceptable salt or hydrate thereof. Furthermore, the invention relates to a pharmaceutical composition comprising the compound of formula (I), and use of the compound in the treatment of diseases related to DP receptor such as asthma.</p>
申请公布号 EP2397476(A3) 申请公布日期 2011.12.28
申请号 EP20110006268 申请日期 2006.07.20
申请人 SHIONOGI & CO., LTD. 发明人 KUGIMIYA, AKIRA;SHICHIJO, MICHITAKA;SHICHIJO, MICHITAKA;HIRAMATSU, YOSHIHARU;ISHIZUKA, NATSUKI
分类号 C07D401/04;A61K31/404;A61K31/4439;A61K31/454;A61P11/06;A61P37/08;A61P43/00;C07D401/14;C07D403/04;C07D405/14;C07D409/14;C07D413/14;C07D417/14 主分类号 C07D401/04
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