MODIFIED 2- AND 3-NUCLEOSIDES AND USE THEREOF TO PRODUCE MEDICINAL AGENT, HAVING HEPATITIS C INHIBITING ACTIVITY

摘要

FIELD: chemistry. ^ SUBSTANCE: invention relates to novel compounds of formula or pharmaceutically acceptable salts thereof, having hepatitis C inhibiting activity, pharmaceutical composition based on said compounds and use thereof to produce a medicinal agent. In compounds of formula (IX) R1 and R2 independently denote H, phosphate or acyl; X denotes O; the base* is a purine base; R12 denotes C(Y3)3; Y3 denotes H and R13 denotes fluorine. ^ EFFECT: improved properties of the compound. ^ 30 cl, 4 dwg, 26 ex