发明名称 |
DELIVERY OF A CD40 AGONIST TO A TUMOR DRAINING LYMPH NODE OF A SUBJECT |
摘要 |
The invention relates to the use of a CD40 agonist for treating cancer, a pre-malignant disorder or an infectious disease, wherein a CD40 agonist is locally administered and targeted to a tumor draining lymph node of a subject. Optionally, a CD40 agonist is formulated in a slow-release formulation. Optionally, a CTL-activating peptide is further administered.
|
申请公布号 |
US2011311525(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
US200913061366 |
申请日期 |
2009.08.31 |
申请人 |
HERBERT-FRANSEN MARIEKE FERNANDE;MELIEF CORNELIS JOSEPH MARIA;ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC |
发明人 |
HERBERT-FRANSEN MARIEKE FERNANDE;MELIEF CORNELIS JOSEPH MARIA |
分类号 |
A61K39/395;A61K31/7052;A61K38/02;A61P35/00 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|