| 发明名称 |
STAT3 INHIBITORS |
| 摘要 |
Small molecule inhibitors of Stat3 and their derivatives are disclosed. Also described are methods to inhibit cell growth by use of Stat3 inhibitors, and the use of Stat3 inhibitors for the prevention and/or treatment of cancer. Further, inhibitors of Stat3 that also do not inhibit Stat1 are described as well as their derivatives. Methods of screening additional compounds for Stat3 inhibition activity and/or non-inhibition of Stat1 activity are also described herein. |
| 申请公布号 |
US2011312984(A1) |
申请公布日期 |
2011.12.22 |
| 申请号 |
US20090996073 |
申请日期 |
2009.06.03 |
| 申请人 |
TWEARDY DAVID J.;HUANG WANZHI;KASEMBELI MOSES M. |
发明人 |
TWEARDY DAVID J.;HUANG WANZHI;KASEMBELI MOSES M. |
| 分类号 |
A61K31/192;A61K31/195;A61K31/352;A61K31/357;A61K31/427;A61K31/513;A61P1/00;A61P1/18;A61P11/06;A61P17/06;A61P25/00;A61P27/02;A61P31/12;A61P35/00;C12N5/071;C12N5/09 |
主分类号 |
A61K31/192 |
| 代理机构 |
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