发明名称 |
DPYD GENE VARIANTS AND USE THEREOF |
摘要 |
Variants in DPYD gene are disclosed which can result in abnormal synthesis of DPD proteins and alteration of DPD activities. The invention provides methods for detecting the newly discovered genetic variants. The DPD genetic variants of the invention can be used as biomarkers in predicting toxicity to 5-FU and other drugs metabolized by the DPD enzyme. |
申请公布号 |
US2011311972(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
US201113104827 |
申请日期 |
2011.05.10 |
申请人 |
WAGNER SUSANNE;JENNIFER POTTER;MYRIAD GENETICS, INCORPORATED |
发明人 |
WAGNER SUSANNE;JENNIFER POTTER |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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