NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS
摘要
The disclosure relates to amide derivatives of formula (I) and a pharmaceutically acceptable salt thereof which selectively and effectively inhibit the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor (EGFR) and also prevents the development of drug resistance caused by the mutation of EGFR tyrosine kinase, a pharmaceutical composition comprising same as an active ingredient, and uses thereof in the manufacture of a medicament.
申请公布号
NZ582412(A)
申请公布日期
2011.12.22
申请号
NZ20080582412
申请日期
2008.06.05
申请人
HANMI HOLDINGS CO., LTD.
发明人
LEE, CHANG GON;KIM, MAENG SUP;LEE, KWANG-OK;CHA, MI YOUNG;KIM, MI RA;JUNG, YOUNG HEE;KIM, SE YOUNG;BANG, KEUKCHAN;PARK, BUM WOO;CHOI, BO IM;CHAE, YUN JUNG;KO, MI YOUNG;KIM, HAN KYONG;AHN, YOUNG-GIL;LEE, GWAN SUN