| 摘要 |
<p>The present invention provides methods of identifying an agent that modulates PRPK, TPRKB, OSGEP, LAGE3 and its homologs, PRPK/TPRKB complex, and/or KEOPS complex. The present invention also provides compositions of such agents and methods of treating a disease, disorder, or condition associated with PRPK, TPRKB, OSGEP, LAGE3 and its homologs family (CT antigens), PRPK/TPRKB complex, and/or KEOPS complex using such an agent or composition.</p> |
| 申请人 |
MAKOTO LIFE SCIENCES, INC.;PARK, EUN, SUN;PELISH, HENRY, E.;CLARKE, ASTRID, S.;WILLIAMS, GRACE, L.;CASTALDI, MARIA, PAOLA;AREFOLOV, ALEXANDER;RING, JENNIFER, E.;SHAIR, MATTHEW, D.;KING, RANDALL, W. |
发明人 |
PARK, EUN, SUN;PELISH, HENRY, E.;CLARKE, ASTRID, S.;WILLIAMS, GRACE, L.;CASTALDI, MARIA, PAOLA;AREFOLOV, ALEXANDER;RING, JENNIFER, E.;SHAIR, MATTHEW, D.;KING, RANDALL, W. |
