发明名称 |
Contrast agent, useful for molecular ultrasound imaging, comprises a coupling substance e.g. spiegelmers bound to microbubbles |
摘要 |
<p>#CMT# #/CMT# Contrast agent comprises a coupling substance bound to microbubbles, where the coupling substance binds selectively to an A- and/or B-domain of a carcinoembryonic antigen-related cell adhesion molecule 1. #CMT# : #/CMT# An independent claim is included for an ultrasound imaging comprising injecting the contrast agent into a bloodstream of a human or animal body. #CMT#USE : #/CMT# The contrast agent is useful for molecular ultrasound imaging. #CMT#ADVANTAGE : #/CMT# The contrast agent provides the molecular ultrasound image without producing any undesirable reactions in a target tissue. #CMT#BIOLOGY : #/CMT# Preferred Components: The coupling substance is formed by monoclonal antibody (mAb). The mAb is an antibody of the type mAb B3. #CMT#ORGANIC CHEMISTRY : #/CMT# The coupling substance is aptamers, spiegelmers and/or anticalins. #CMT#EXAMPLE : #/CMT# None given.</p> |
申请公布号 |
DE102010024643(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
DE20101024643 |
申请日期 |
2010.06.22 |
申请人 |
SIEMENS AKTIENGESELLSCHAFT |
发明人 |
ERGUEN, SUELEYMAN, PROF.;FEHRE, JENS;NANKE, RALF, DR.;SINGER, BERNHARD, DR. |
分类号 |
A61K49/22 |
主分类号 |
A61K49/22 |
代理机构 |
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代理人 |
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