发明名称 |
NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION |
摘要 |
Provided is a nucleic acid complex comprising a nucleic acid and a highly branched cyclic dextrin, wherein the highly branched cyclic dextrin is a glucan with a degree of polymerization of 50 to 5000 having an inner branched cyclic structure portion formed from alpha-1,4-glucoside bonds and at least one alpha-1,6-glucoside bond, and an outer branched structure portion bound to the inner branched cyclic structure portion. The complex can be used in the manufacture of medicaments for siRNA delivery.
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申请公布号 |
NZ584841(A) |
申请公布日期 |
2011.12.22 |
申请号 |
NZ20080584841 |
申请日期 |
2008.11.06 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD.;HIROFUMI TAKEUCHI |
发明人 |
TAKEUCHI, HIROFUMI;TOZUKA, YUICHI;HIRA, YASUYUKI;TOYOBUKU, HIDEKAZU |
分类号 |
A61K9/127;A61K47/40;A61K47/48;A61K48/00;C12N15/87 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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