发明名称 FUSED BICYCLIC HETEROARYL DERIVATIVES
摘要 Disclosed are fused bicyclic heteroaryl derivatives represented by general formula (I), such as 3-{ [6-(3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy} benzoic acid, or pharmaceutically acceptable salts thereof. Also disclosed is the use of the compounds of general formula (I) for treating diabetes, activating PPAR-gamma, improving carbohydrate or lipid metabolism, improving insulin resistance, inhibiting inflammation, inhibiting the growth of cancer cells, for the treatment and/or prevention of hyperglycemia, hyperlipidemia, adiposity, impaired glucose tolerance, insulin resistance, impaired fasting glucose hypertension, fatty liver, non-alcoholic steatohepatitis, diabetic complications, arteriosclerosis, atherosclerosis, gestational diabetes mellitus or polycystic ovary syndrome.
申请公布号 NZ580588(A) 申请公布日期 2011.12.22
申请号 NZ20080580588 申请日期 2008.04.02
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 SHIMADA, KOUSEI;ONISHI, YOSHIYUKI;MORI, MAKOTO;TOKUMARU, ERI
分类号 A61P3/04;A61K31/4184;A61K31/437;A61P1/04;A61P1/16;A61P1/18;A61P3/06;A61P3/10;A61P7/00;A61P7/10;A61P9/00;A61P9/10;A61P9/12;A61P11/06;A61P15/00;A61P17/04;A61P17/06;A61P17/10;A61P17/16;A61P19/10;A61P25/28;A61P27/02;A61P27/14;A61P29/00;A61P35/00;A61P43/00;C07D235/12;C07D405/12;C07D471/04 主分类号 A61P3/04
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