发明名称 POLYMORPHS OF A MGLUR5 RECEPTOR ANTAGONIST
摘要 Disclosed are mono and hemi sulphate salts of 2-chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine. Crystalline forms of these salts are also disclosed as well as processes for producing them. The use of the salts or crystalline forms for treating acute and/or chronic neurological disorders, in particular anxiety, or for the treatment of chronic and acute pain, protection against liver damage, failure whether drug or disease induced, urinary incontinence, obesity, Fragile-X or Autism.
申请公布号 NZ577440(A) 申请公布日期 2011.12.22
申请号 NZ20070577440 申请日期 2007.12.11
申请人 F. HOFFMANN-LA ROCHE AG 发明人 MOOG, REGINA;CLEARY, THOMAS P;GLOMME, ALEXANDER;GRASSMANN, OLAF;KUANG, SHAN-MING;MEIER, ROLAND;MILLER, DOREEN;ROHRER, FRANZISKA E;YANG, JASON
分类号 C07D401/06;A61K31/4439;A61P25/00 主分类号 C07D401/06
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