发明名称 |
A PROCESS FOR THE PREPARATION OF NATEGLINIDE |
摘要 |
<p>The present invention relates to a process for the preparation of substantially pure nateglinide of formula (I), substantially free from the cis-isomer and L-enantiomer and preparation of enantiomerically pure nateglinide form B, directly from the hydrolysis of a (-)-N-(trans-4-isopropylcyclohexyl-1-carbonyl)-D-phenylalanine alkyl ester in a ketonic solvent or water or mixture thereof.</p> |
申请公布号 |
CA2802455(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
CA20112802455 |
申请日期 |
2011.06.14 |
申请人 |
CIPLA LIMITED |
发明人 |
KANKAN, RAJENDRA NARAYANRAO;RAO, DHARMARAJ RAMACHANDRA;BIRARI, DILIP RAMDAS |
分类号 |
C07C231/12;C07C233/63 |
主分类号 |
C07C231/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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