发明名称 SINGLE ENANTIOMER BETA AGONISTS METHOD FOR PRODUCTION AND USE THEREOF AS A MEDICAMENT
摘要 Disclosed is an enantiomerically pure, solvent-free, crystalline form of a compound of formula 1-base e.g. N-(5-{ 2-[1,1-dimethyl-3-(2-oxo-4,4-dipropyl-4H-benzo[d][1,3]oxazin-1- yl)-propylamino]-1-hydroxy-ethyl} -2-hydroxy-phenyl)-methanesulphonamide wherein R1 and R2 which may be identical or different, denote ethyl or propyl, or together denote -CH2-CH2, -CH2-CH2-CH2, -CH2-CH2-CH2-CH2 or -CH2-CH2-CH2-CH2-CH2- and R3 represents hydrogen, fluorine, chlorine, OH, methyl, ethyl, methoxy or ethoxy for the treatment of a respiratory condition.
申请公布号 NZ575567(A) 申请公布日期 2011.12.22
申请号 NZ20070575567 申请日期 2007.08.21
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 KONETZKI, INGO;SIEGER, PETER
分类号 C07D265/18;A61K31/536;A61P11/06;A61P11/08 主分类号 C07D265/18
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