| 发明名称 |
P38 MAP KINASE INHIBITORS |
| 摘要 |
The present disclosure relates to compounds of formula (I): which are inhibitors of p38 mitogen-activated protein kinase enzymes, particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD |
| 申请公布号 |
US2011312963(A1) |
申请公布日期 |
2011.12.22 |
| 申请号 |
US200913139010 |
申请日期 |
2009.12.11 |
| 申请人 |
ITO KAZUHIRO;STRONG PETER;RAPEPORT WILLIAM GARTH;MURRAY PETER JOHN;KING-UNDERWOOD JOHN;WILLIAMS JONATHAN GARETH;ONIONS STUART THOMAS;JOLY KEVIN;CHARRON CATHERINE ELISABETH |
发明人 |
ITO KAZUHIRO;STRONG PETER;RAPEPORT WILLIAM GARTH;MURRAY PETER JOHN;KING-UNDERWOOD JOHN;WILLIAMS JONATHAN GARETH;ONIONS STUART THOMAS;JOLY KEVIN;CHARRON CATHERINE ELISABETH |
| 分类号 |
A61K31/4439;A61K31/444;A61K31/4545;A61K31/496;A61K31/506;A61K31/5377;A61P1/04;A61P1/18;A61P3/00;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P27/02;A61P27/14;A61P29/00;A61P35/00;A61P35/04;A61P37/08;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D413/14 |
主分类号 |
A61K31/4439 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
