发明名称 Methods and Compositions Relating to CCR5 Antagonist, IFN-Gamma and IL-13 Induced Inflammation
摘要 The present invention includes compositions and methods for the treatment of Th1 and/or Th2 mediated inflammatory diseases, relating to inhibiting CCR5. This is because the present invention demonstrates, for the first time, that expression of IFN-γ, IL-13, and CCR5, mediates and/or is associated with Th1 and/or Th2 inflammatory diseases and that inhibiting CCR5 treats, and even prevents, the diseases. Thus, the invention relates to the novel discovery that inhibiting CCR5 treats and prevents Th1 and/or Th2 mediated inflammatory disease.
申请公布号 US2011311560(A1) 申请公布日期 2011.12.22
申请号 US201113084239 申请日期 2011.04.11
申请人 MA BING;ELIAS JACK A. 发明人 MA BING;ELIAS JACK A.
分类号 A61K31/439;A61K;A61K39/395;A61P11/00;A61P37/06;C07K16/28 主分类号 A61K31/439
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