发明名称 |
INHALABLE PARTICLES COMPRISING TIOTROPIUM |
摘要 |
The present invention relates to inhalable particles comprising a stabilized amorphous form of tiotropium with a stabilizing agent. It also relates to inhalable particles comprising a stabilized amorphous form of tiotropium with a stabilizing agent mixed with one or more coarse excipients having a mean particle size of 15 to 250 μm. It also relates to a pharmaceutical composition comprising the inhalable particles of the invention, to a process for their preparation, and to their use for the preparation of a medicament for the treatment of asthma or chronic obstructive pulmonary disease (COPD). |
申请公布号 |
US2011311618(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
US200913122134 |
申请日期 |
2009.10.02 |
申请人 |
AMIGHI KARIM;SERENO GUERRA ANTONIO;LABORATORIOS LICONSA, S.A. |
发明人 |
AMIGHI KARIM;SERENO GUERRA ANTONIO |
分类号 |
A61K31/439;A61K9/14;A61K9/48;A61P11/00;A61P11/06 |
主分类号 |
A61K31/439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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