发明名称 LOXOPROFEN DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME
摘要 There is provided a novel loxoprofen derivative that has no side effect such as a gastrointestinal disorder and also has excellent anti-inflammatory and analgesic effects and is represented by the following formula (I) or (II): (wherein R 1 and R 2 each represent a halogen atom or a substituted or unsubstituted phenyl group) or a pharmacologically acceptable salt thereof. In the derivative, the halogen atom is selected from a chlorine atom, a bromine atom, a fluorine atom, and an iodine atom, and a substituent of the substituted phenyl group is a halogen atom, a hydroxyl group, a substituted or unsubstituted lower alkyl group, a lower alkylthio group, a lower alkoxy group, a nitro group, an amino group, or a carboxyl group.
申请公布号 KR20110137321(A) 申请公布日期 2011.12.22
申请号 KR20117022258 申请日期 2010.02.18
申请人 NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY;LTT BIO-PHARMA CO., LTD. 发明人 MIZUSHIMA TORU;OHTSUKA MASAMI;OKAMOTO YOSHINARI;YAMAKAWA NAOKI
分类号 C07C59/88;A61K31/192;A61P29/00;C07C59/56 主分类号 C07C59/88
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