TARGETING TUMOR ASSOCIATED MACROPHAGES USING BISPHOSPHONATE-LOADED PARTICLES
摘要
Provided herein are compositions including particles that comprise a bisphosphonate compound and a tumor specific targeting peptide or peptidomimetic. Also provided herein are methods of reducing tumor associated macrophages and methods of treating cancer with said compositions.
申请公布号
WO2011159951(A2)
申请公布日期
2011.12.22
申请号
WO2011US40776
申请日期
2011.06.16
申请人
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE;SMITH, JEFF;SHARMA, GAURAV