| 发明名称 |
AT1-RECEPTOR ANTAGONIST FOR PREVENTING AND TREATING POSTISCHEMIC RENAL FAILURE AND FOR PROTECTING ISCHEMIC KIDNEY |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a specific AT1-receptor antagonist for treating (acute and chronic) postischemic renal failure and for protecting ischemic kidney. <P>SOLUTION: The compound (S)-N-(1-carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2'(1H-tetrazol-5-yl)biphenyl-4-yl-methyl]amine (valsartan) of the formula or its salt, in particular its pharmaceutically acceptable salt thereof, can be used for treating (acute and chronic) postischemic renal failure and for protecting the ischemic kidney. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2011256195(A) |
申请公布日期 |
2011.12.22 |
| 申请号 |
JP20110176948 |
申请日期 |
2011.08.12 |
| 申请人 |
NOVARTIS AG |
发明人 |
HUMKE ULRICH |
| 分类号 |
A61K45/00;C07D401/10;A61K31/00;A61K31/40;A61K31/41;A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/4184;A61K31/4188;A61K31/437;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/455;A61K31/47;A61K31/4709;A61K31/472;A61K31/4725;A61P9/10;A61P13/00;A61P13/12;C07D257/04;C07D401/14;C07D403/10;C07D405/06;C07D409/06;C07D471/04 |
主分类号 |
A61K45/00 |
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