发明名称 |
PROCESS FOR PRODUCTION OF HEMATOPOIETIC STEM CELL |
摘要 |
Disclosed is an agent for amplifying a hematopoietic stem cell and/or a hematopoietic progenitor cell, which is useful as a therapeutic method for various hematopoietic diseases and is also useful for the improvement in the efficiency of gene transfer into a hematopoietic stem cell in a gene therapy. Also disclosed is a process for producing a hematopoietic stem cell and/or a hematopoietic progenitor cell, which is characterized by culturing a hematopoietic stem cell in the presence of a compound represented by formula (I) (wherein R1 to R6 are as defined in the description), a tautomer or pharmaceutically acceptable salt thereof, or a solvate of the compound, the tautomer or the pharmaceutically acceptable salt to amplify the cell. |
申请公布号 |
WO2011158806(A1) |
申请公布日期 |
2011.12.22 |
申请号 |
WO2011JP63537 |
申请日期 |
2011.06.13 |
申请人 |
NISSAN CHEMICAL INDUSTRIES, LTD.;NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY;NISHINO, TAITO;IWAMA, ATSUSHI |
发明人 |
NISHINO, TAITO;IWAMA, ATSUSHI |
分类号 |
C12N5/078;A61K31/122;A61P43/00;C12N5/071;C12N5/10 |
主分类号 |
C12N5/078 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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