<p>The present invention relates to the use of thrombomodulin analogues for the manufacture of a medicament for the treatment of coagulopathy with hyperfibrinolysis, such as haemophilia disorders. These thrombomodulin analogues exhibit at therapeutically effective dosages an antifibrinolytic effect. Novel protein modifications together with methods for their identification are disclosed.</p>
申请公布号
WO2011157283(A1)
申请公布日期
2011.12.22
申请号
WO2010EP07632
申请日期
2010.12.15
申请人
PAION DEUTSCHLAND GMBH;PETERSEN, KARL-UWE;NESHEIM, MICHAEL ERNEST;FOLEY, JONATHAN HERBERT
发明人
PETERSEN, KARL-UWE;NESHEIM, MICHAEL ERNEST;FOLEY, JONATHAN HERBERT