摘要 |
The present invention relates to an anti-cancer pharmaceutical composition comprising phenformin or a pharmaceutically acceptable salt thereof and 2-deoxy-D-glucose as active ingredients, having anticancer activity. The pharmaceutical composition shows far superior anticancer effects through the synergistic action between each active ingredient over the case using a single active ingredient, and can reduce the side effects caused by drugs due to the decrease of dose. In addition, the present invention can remarkably reduce side effects such as lactic acidosis caused by phenformin through delayed release or delayed administration of active ingredients. Particularly, the pharmaceutical composition according to the present invention also has increased compliance of a patient, and thus can be very useful for treating various types of cancers. |
申请人 |
HANALL BIOPHARMA CO., LTD.;KIM, SUNG-WUK;JUN, SUNG-SOO;MIN, CHANG-HEE;KOO, JA-SEONG;KIM, JIN-WOOK;KIM, YONG-EUN;SUN, SANG-OUK |
发明人 |
KIM, SUNG-WUK;JUN, SUNG-SOO;MIN, CHANG-HEE;KOO, JA-SEONG;KIM, JIN-WOOK;KIM, YONG-EUN;SUN, SANG-OUK |