发明名称 COMPOUNDS AND METHODS FOR MODULATING INTERACTION BETWEEN PROTEINS AND TARGET NUCLEIC ACIDS
摘要 Provided herein are antisense compounds and methods for recruiting one or more non-cleaving protein to a target nucleic acid in a cell. In certain instances such recruitment of a non-cleaving protein alters the function or activity of the target nucleic acid. In certain such instances, the target nucleic acid a pre-mRNA and the recruitment of the non-cleaving protein results in a change in splicing of the pre-mRNA.
申请公布号 WO2011159836(A2) 申请公布日期 2011.12.22
申请号 WO2011US40581 申请日期 2011.06.15
申请人 ISIS PHARMACEUTICALS, INC.;COLD SPRING HARBOR LABORATORY;RIGO, FRANK;BENNETT, C., FRANK;KRAINER, ADRIAN, R.;HUA, YIMIN 发明人 RIGO, FRANK;BENNETT, C., FRANK;KRAINER, ADRIAN, R.;HUA, YIMIN
分类号 A61K48/00 主分类号 A61K48/00
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