发明名称 |
Methods for detecting a mycobacterium tuberculosis infection |
摘要 |
<p>Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8+ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods can also include detecting Mtb polypeptides and polynucleotides. Reagents for the detection of an Mtb infection are also disclosed.</p> |
申请公布号 |
EP2397853(A2) |
申请公布日期 |
2011.12.21 |
申请号 |
EP20110178706 |
申请日期 |
2007.03.14 |
申请人 |
OREGON HEALTH AND SCIENCE UNIVERSITY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA D.B.A THE DEPARTMENT OF VETERANS AFFAIRS |
发明人 |
LEWINSOHN, DAVID;LEWINSOHN, DEBORAH |
分类号 |
G01N33/569 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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