ANTI-INFLAMMATORY SKIN COMPOSITION CONTAINING CAESAPINIA SAPPAN, AND CELL-TRANSDUCING HEAT SHOCK PROTEIN 27 FUSION PROTEIN

摘要

PURPOSE: An external use skin composition containing cell permeable HSP27 and Caesalpinia sappan L. extract is provided to suppres edema and cytokine expression. CONSTITUTION: An external use skin composition for anti-inflammation contains 0.001-50 wt% of Caesapinia sappan L. extract and cell permeable HSP27 fusion protein. The cell permeable HSP27 fusion protein is Pep-HSP27 fusion protein. The external use skin composition is manufactured in the form of a lotion, gel, water soluble liquid, cream, essence, water-in-oil type or oil-in-water type formulation. The composition is administered in 0.0001-100 mg/kg a day.