发明名称 USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION
摘要 The present invention relates to a method for complexation of a chelate with a radionuclide, advantageously gallium, the complexation being carried out advantageously at ambient temperature without heating, by adding the radionuclide to the chelate in a buffer solution, the buffer of this solution comprising between two and five functions for coordination with the radionuclide, each coordination function being independently chosen from a carboxylic acid function and a hydroxyl function, on the condition that the buffer comprises at least one carboxylic acid function and at most two carboxylic acid functions. It also relates to the injectable solution obtained.
申请公布号 EP2396040(A1) 申请公布日期 2011.12.21
申请号 EP20100703282 申请日期 2010.02.11
申请人 GUERBET 发明人 PORT, MARC;MEDINA, CHRISTELLE
分类号 A61K51/00;A61K103/34;A61P43/00;C07F5/00 主分类号 A61K51/00
代理机构 代理人
主权项
地址