发明名称 |
Substituted 4-amino-benzylpiperidine compounds |
摘要 |
This invention provides 4-amino-1-benzylpiperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome, asthma and chronic obstructive pulmonary disease, using such compounds. |
申请公布号 |
US8080565(B2) |
申请公布日期 |
2011.12.20 |
申请号 |
US20080074889 |
申请日期 |
2008.03.06 |
申请人 |
MAMMEN MATHAI;WILSON RICHARD;DUNHAM SARAH;HUGHES ADAM;HUSFELD CRAIG;JI YU-HUA;LI LI;MISCHKI TREVOR;STERGIADES IOANNA;OARE DAVID;THERAVANCE, INC. |
发明人 |
MAMMEN MATHAI;WILSON RICHARD;DUNHAM SARAH;HUGHES ADAM;HUSFELD CRAIG;JI YU-HUA;LI LI;MISCHKI TREVOR;STERGIADES IOANNA;OARE DAVID |
分类号 |
A61K31/445;A61P13/10;C07D401/02;C07D401/12;C07D401/14;C07D405/14 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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