摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to a method of producing 4-(dimethylamino)-2-butinyl alkanoates, which are of interest in synthesis of physiologically active substances. The method involves reaction of propargyl alkanoates with N,N,N1,N1-tetramethyl methane diamine in the presence of a Sm(NO3)26H2O catalyst at temperature 50-100C, preferably 80C, and atmospheric pressure for 5-7 hours. Output of 4-(dimethylamino)-2-butinyl alkanoates is equal to 56-96%. ^ EFFECT: high output of end product. ^ 1cl, 9 ex |