A METHOD OF CONTROLLING THE BROMINATION OF THIOPHENE DERIVATIVES
摘要
<p>Provided is a method for regioselective synthesis of a bromoalkylthiophene with improved yield. A 3-alkylthiophene is activated at -78not;C with n-BuLi for about 1.5 hour and then reacted with bromine to give a bromoalkylthiophene with good regioselectivity:</p>
申请公布号
WO2011155679(A1)
申请公布日期
2011.12.15
申请号
WO2010KR08891
申请日期
2010.12.13
申请人
GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY;LEE, JAE-SUK;ASHRAF, A. EL-SHEHAWY;MIN, JOON-KEUN;NABIHA, I. ABDO
发明人
LEE, JAE-SUK;ASHRAF, A. EL-SHEHAWY;MIN, JOON-KEUN;NABIHA, I. ABDO
