发明名称 |
NEAR FIELD-ENHANCED FLUORESCENCE SENSOR CHIP |
摘要 |
Disclosed is an SPFS sensor chip by which an antigen-antibody reaction or fluorescence can be detected at the maximum efficiency. The SPFS sensor chip, which comprises a transparent substrate, a metal film, an SAM, a solid phase layer having a three-dimensional structure and a ligand, is characterized in that, in said sensor chip, the fluctuation rate represented by the following formula is 0-30% inclusive: [half-width (a)-half width (ß)]/half width (ß)×100 [wherein half-width (a) is obtained from a graph that is drawn by plotting the intensity of reflected light of light entering at a definite angle from one surface of said transparent substrate, said surface not being in contact with the metal film and said reflected light intensity being measured with a light intensity detector placed on the opposite surface side of the transparent substrate, against the angle; and half width (ß) represents the half width of the sensor chip comprising the transparent substrate and the metal film]. |
申请公布号 |
WO2011155435(A1) |
申请公布日期 |
2011.12.15 |
申请号 |
WO2011JP62919 |
申请日期 |
2011.06.06 |
申请人 |
KONICA MINOLTA HOLDINGS, INC.;KAYA, TAKATOSHI;HIKAGE, NAOKI;NINOMIYA, HIDETAKA |
发明人 |
KAYA, TAKATOSHI;HIKAGE, NAOKI;NINOMIYA, HIDETAKA |
分类号 |
G01N21/64;G01N33/543 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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