METHODS FOR THE DEVELOPMENT OF VACCINES BASED ON OLIGOSACCHARIDE-OLIGONUCLEOTIDE CONJUGATES
摘要
Described herein are oligosaccharide-oligonucleotide conjugates useful as vaccines against one or more human or veterinary therapeutic indications, and methods of synthesizing and identifying them. The conjugates may be identified using non-human antibodies as binding targets, thereby expanding the power and scope of the invention. Efficacious conjugates may be identified through an iterative.
申请公布号
WO2011156690(A2)
申请公布日期
2011.12.15
申请号
WO2011US39949
申请日期
2011.06.10
申请人
BRANDEIS UNIVERSITY;KRAUSS, ISAAC, J.;HEDSTROM, LIZBETH, K.;MACPHERSON, IAIN, S.
发明人
KRAUSS, ISAAC, J.;HEDSTROM, LIZBETH, K.;MACPHERSON, IAIN, S.