Targeted synthetic nanocarriers with pH sensitive release of immunomodulatory agents
摘要
<p>This invention relates to compositions, and related methods, of synthetic nanocarriers that target sites of action in cells, such as antigen presenting cells (APCs), and comprise immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner. Also disclosed are compositions and methods relating to synthetic nanocarriers that encapsulate labile immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner.</p>
申请公布号
AU2010254550(A1)
申请公布日期
2011.12.15
申请号
AU20100254550
申请日期
2010.05.26
申请人
SELECTA BIOSCIENCES, INC.
发明人
ZEPP, CHARLES;GAO, YUN;KEEGAN, MARK J.;BALDWIN, SAM;FU, FEN-NI;JOHNSTON, LLOYD;LIPFORD, GRAYSON B.