| 摘要 |
<p>AN ANTIBODY CAPABLE OF BINDING TO A SPECIFIC REGION OF GLYPICAN 3, AS WELL AS A HUMANIZED ANTIBODY CREATED BASED ON THAT ANTIBODY ARE DISCLOSED. THE ANTI-GPC3 ANTIBODY OF THE INVENTION HAS A HIGHER ADCC ACTIVITY AND CDC ACTIVITY COMPARED WITH THOSE OF A CONVENTIONAL ANTIBODY. THE ANTIBODY OF THE PRESENT INVENTION IS USEFUL AS A CELL GROWTH INHIBITOR, AN ANTICANCER AGENT AND AN AGENT FOR DIAGNOSIS OF CANCERS.</p> |
