| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for efficiently manufacturing 4-halo-3-hydroxy butyl amide. <P>SOLUTION: The method for manufacturing 4-halo-3-hydroxy butyl amide includes following processes: (1) a process of supplying gas to a solution containing 4-halo-3-hydroxy butyronitrile, and (2) a process of amidating the nitrile by putting it in contact with nitrile hydratase in the presence of a metallic salt. <P>COPYRIGHT: (C)2012,JPO&INPIT |
