| 发明名称 |
STEREOSELECTIVE HYDROGENATION OF A KETONE |
| 摘要 |
The present invention relates to a method comprising reducing a ketone of formula I: with an enantioselective hydrogenating agent to form substantially enantiomerically pure alcohol of formula II: where R—R4 and m are as defined herein. The method of the present invention is useful for making CCR2 modulators as wells as precursors CCR2 modulators. |
| 申请公布号 |
US2011306765(A1) |
申请公布日期 |
2011.12.15 |
| 申请号 |
US201013202834 |
申请日期 |
2010.02.23 |
| 申请人 |
HAILE PAMELA A.;SEHON CLARK A.;WANG HUAN |
发明人 |
HAILE PAMELA A.;SEHON CLARK A.;WANG HUAN |
| 分类号 |
C07D471/10;C07D401/06 |
主分类号 |
C07D471/10 |
| 代理机构 |
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| 主权项 |
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| 地址 |
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