发明名称 |
METHOD AND COMPOSITIONS FOR DETERMINING ENZYMATIC ACTIVITY AND SPECIFICITY OF METHYLTRANSFERASES |
摘要 |
The invention provides crystalline O-methyltransferases and isolated non-native O-methyltransferases as well as sets of their structural coordinates. Also provided are methods of predicting the activity or substrate specificity of putative O-methyltransferases, methods of identifying potential substrates of O-methyltransferases, and methods of identifying potential inhibitors of methyltransferases. |
申请公布号 |
US2011306073(A1) |
申请公布日期 |
2011.12.15 |
申请号 |
US201113097617 |
申请日期 |
2011.04.29 |
申请人 |
NOEL JOSEPH P.;ZUBIETA CHLOE;DIXON RICHARD;THE SAMUEL ROBERTS NOBLE FOUNDATION;THE SALK INSTITUTE FOR BIOLOGICAL STUDIES |
发明人 |
NOEL JOSEPH P.;ZUBIETA CHLOE;DIXON RICHARD |
分类号 |
C12Q1/48;C12N9/10;C12N9/96;G06F19/00;G06G7/58 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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