发明名称 |
Mutant Cells Suitable For Recombinant Polypeptide Production |
摘要 |
A mutated bacterial cell producing at least one heterologous polypeptide of interest, wherein said cell has a reduced expression-level of a polypeptide comprising an amino acid sequence at least 70% identical to the sequence shown in SEQ ID NO: 2, when compared with an otherwise isogenic but non-mutated cell; methods for producing said mutated cell; and methods for producing a polypeptide of interest using said mutated cell. SEQ ID NO: 2 represents a putative metalloprotease. |
申请公布号 |
US2011306139(A1) |
申请公布日期 |
2011.12.15 |
申请号 |
US201013203050 |
申请日期 |
2010.02.25 |
申请人 |
NIELSEN ALLAN KENT;RASMUSSEN MICHAEL DOLBERG;BANKE NIELS;NOVOZYMES A/S |
发明人 |
NIELSEN ALLAN KENT;RASMUSSEN MICHAEL DOLBERG;BANKE NIELS |
分类号 |
C12N15/75;C12N1/21;C12N9/00;C12N9/02;C12N9/10;C12N9/14;C12N9/88;C12N9/90 |
主分类号 |
C12N15/75 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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