发明名称 |
PSMA-BINDING AGENTS AND USES THEREOF |
摘要 |
Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis. |
申请公布号 |
EP2318366(A4) |
申请公布日期 |
2011.12.14 |
申请号 |
EP20090803670 |
申请日期 |
2009.07.31 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
POMPER, MARTIN, GILBERT;MEASE, RONNIE, CHARLES;CHEN, YING |
分类号 |
C07D211/34;A61K9/127;A61K31/33;A61K31/44;A61K51/00;A61P9/00;A61P9/10;A61P35/00;C07C275/00;C07D213/61;C07D213/74;C07D213/82 |
主分类号 |
C07D211/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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