PURIFICATION OF TAXANES AND TAXANE MIXTURES USING POLYETHYLENEIMINE-BONDED RESINS
摘要
This invention is directed to a method for isolating and /or purifying one or more taxanes from materials comprising taxanes. In one embodiment, the method comprises the steps of: (a) treating a taxane containing material with an amino containing material attached to a solid matrix, such as a polyethyleneimine-bonded silica chromatographic resin; (b) eluting the desired taxane compound from the resin; and (c) recovering the eluted taxane compound.
申请公布号
CA2519474(C)
申请公布日期
2011.12.13
申请号
CA20042519474
申请日期
2004.03.17
申请人
NATURAL PHARMACEUTICALS, INC.
发明人
JOHNSON, JAMES H.;SAMBANDAM, T. G.;HAND, BARRY J.;HOWE, CHRISTOPHER D.;FRANKE, ROLAND R.;BUCHER, BRIAN A.;JUCHUM, JOHN S.;GALLAGHER, REX T.;PLANTE, MARC A.;DESIMONE, EDWARD M., III.;YANG, DONG S.