发明名称 COMPOSITION COMPRISING SESQUITERPENE COMPOUNDS FOR PREVENTION OR TREATMENT OF DEGENERATIVE BRAIN DISEASES
摘要 PURPOSE: A composition containing sesquiterpene compound for preventing or treating neurodegenerative diseases is provided to suppress deformation of alpha-synuclein. CONSTITUTION: A composition for preventing or treating neurodegenerative diseases contains sesquiterpene of isozaluzanin C, magnolialide, santamarine, lucentolide, 1beta-hydroxyarbusculin A, and methyl 1beta, 2beta, 6 alpha-trihydroxy-5alpha,7alphaH-eudesma-4(15),11(13)-dien-12-oate as an active ingredient. The neurodegenerative diseases are Parkinson's disease, Alzheimer's disease, or Lewy body dementia. The sesquiterpene compound is isolated from chloroform of Laurus nobilis L.
申请公布号 KR101092620(B1) 申请公布日期 2011.12.13
申请号 KR20100055114 申请日期 2010.06.10
申请人 SNU R&DB FOUNDATION 发明人 MAR, WOONG CHON;SHIN, JONG HEON;HAM, AH ROM
分类号 A61K31/7048;A61K31/19;A61K31/34;A61P25/00 主分类号 A61K31/7048
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