发明名称 |
System and method of chemical imaging using pulsed laser excitation and time-gated detection to determine tissue margins during surgery |
摘要 |
System and method for differentiating tissue margins in a biological sample using pulsed laser excitation and time-gated detection. A region containing a biological tissue is irradiated with substantially monochromatic pulsed laser light to thereby produce Raman scattered photons. The Raman scattered photons are detected using time-gated detection to thereby obtain a Raman spectroscopic image from the irradiated region characteristic of either a neoplastic portion or a non-neoplastic portion of the region containing the biological tissue. A boundary between a neoplastic portion and a non-neoplastic portion is differentiated and the boundary location in the Raman spectroscopic image is displayed. |
申请公布号 |
US8078268(B2) |
申请公布日期 |
2011.12.13 |
申请号 |
US20090565279 |
申请日期 |
2009.09.23 |
申请人 |
MAIER JOHN S.;STEWART SHONA;COHEN JEFFREY;NELSON MATTHEW;TREADO PATRICK J;CHEMIMAGE CORPORATION |
发明人 |
MAIER JOHN S.;STEWART SHONA;COHEN JEFFREY;NELSON MATTHEW;TREADO PATRICK J |
分类号 |
A61B6/00 |
主分类号 |
A61B6/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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