发明名称 MEK INHIBITORS AND USE THEREOF
摘要 Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
申请公布号 UA96742(C2) 申请公布日期 2011.12.12
申请号 UA20080005914 申请日期 2006.10.05
申请人 EXELIXIS, INC. 发明人 AAY, NAING;ANAND, NEEL KUMAR;BOWLES OWEN JOSEPH;BUSSENIUS, JOERG;COSTANZO, SIMONA;CURTIS, JEFFRY KIMO;DUBENKO LARISA;JOSHI ANAGHA ABHIJIT;KENNEDY, ABIGAIL R.;KIM, ANGIE INYOUNG;KOLTUN ELENA;MANALO, JEAN-CLAIRE LIMUN;PETO, CSABA J.;RICE, KENNETH D.;TSANG, TSZE H.;DEFINA, STEVEN CHARLES;BLAZEY, CHARLES M.
分类号 C07D205/04;A61K31/397;C07D205/06;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D405/12;C07D409/06;C07D409/12;C07D413/14;C07D417/12;C07D471/04 主分类号 C07D205/04
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