发明名称 AMINOACYL DERIVATIVE PRODRUGS AND PREPARATIONS FOR TREATING THROMBOEMBOLIC DISEASES
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to a compound of formula in which R1 means hydrogen or alkyl with 1-4 carbon atoms, R2 means hydrogen and L means an alkandiyl group with 1-4 carbon atoms, one CH2-group in which can be substituted by with oxygen atom or a group of formula: or in which * means a conjunction with nitrogen atom, R3 means hydrogen, methyl, propane-2-yl, propane-1-yl, imidazol-4-ylmethyl, hydroxymethryl or 4-aminobutan-4-yl, or R3 is connected with R1 together with which forms (CH2)3- or (CH2)4- -group, R4 means hydrogen or methyl, R5 means alkyl with 1-4 carbon atoms, and R6 means hydrogen or alkyl with 1-4 carbon atoms, and also to its salt and to a method of preparing it. ^ EFFECT: there are prepared new compounds which can find application in medicine for treating and/or preventing diseases, first of all thromboembolic diseases. ^ 5 cl, 4 tbl, 23 ex
申请公布号 RU2435768(C2) 申请公布日期 2011.12.10
申请号 RU20080136769 申请日期 2007.02.06
申请人 BAJER SHERING FARMA AKTSIENGEZEL'SHAFT 发明人 LERKHEN KHANS-GEORG;KRENTS URSULA;SHLEMMER KARL-KHAJNTS;PERTSBORN EHLIZABET;KEL'DENIKH JORG
分类号 A61K31/422;A61K31/5377;A61P7/02;C07D413/14 主分类号 A61K31/422
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